Rodrguez-Archilla A, Raissouni T. Randomized clinical trial of the effectiveness of complementary therapies for recurrent aphthous stomatitis. Data suggest that black cohosh has a direct effect on the neurotransmitters and receptors involved in anxiety. 2021 Jan 21;22(3):1032. doi: 10.3390/ijms22031032. Black cohosh side effects include: Stomach upset Rash Cramping Headaches Vaginal spotting or bleeding 2 Potential soy side effects include: This is Vitamin B2, and its often used in dietary supplements. Rhubarb supplements have not been approved by the FDA for medical use. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. Phytoestrogens mimic estrogen in the body by binding to estrogen receptors. What are the side effects of Rhapontic rhubarb? Rhubarb contains oxalate, which causes illness or death when large quantities are ingested. Rhubarb can be found in various forms, usually made from the roots and rhizomes of Chinese rhubarb [3, 4]: The below doses may not apply to you personally. Jiao, D. H. [Clinical research on the hemostatic effect of rhubarb on peptic ulcer with acute bleeding]. Combined with dialysis, a Chinese medication with rhubarb (Xinqingning) reduced the buildup of toxins in the blood; it helped slow the progression of chronic kidney failure in 57 patients. which enables users to obtain detailed information and reports based on their genome. There are also several inactive ingredients included: This is a plant which can only be found in the Rila Mountain Range in south-western Bulgaria. Scientists tested the rhapontic rhubarb extract in a placebo-controlled trial and found that it reduced menopause symptoms significantly more than placebo over 12 weeks ( Alternative Therapies in Health and Medicine, Jan-Feb., 2009). Qian GP. Rhubarb is known for its very sour, celery-like stalks, which vary in color, from pale pink to pale green. Rhubarb might harm the liver. Zhang, J. H., Li, L. S., and Zhang, M. Clinical effects of rheum and captopril on preventing progression of chronic renal failure. Gut 1993;34(8):1099-1101. He found a way to merge his two biggest passionswriting and healthand use them for noble purposes. The information contained in this website is provided for general informational purposes only. Concern over the safety and effectiveness of hormone replacement therapy for relieving these symptoms has caused many women to seek alternative medical treatments. Rash. In women's health, these medicinal rhubarb species are speci cally used for the treatment of constipation in pregnant women.7,8 In all cases, the presence of emodin or rhein in these preparations may increase the risk of unwanted side effects in the breast and endome- Kwan TH, Tong MK, Leung KT, et al. . In vitro binding of bile salt to rhubarb stalk powder. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Careers. What is the structural formula of ethyl p Nitrobenzoate? Sun, Y., Chen, B., and Jia, Q. View abstract. Taking rhubarb with a medication that can harm the kidneys might increase the risk of kidney damage. This increases the fluid content and volume in the stool, easing constipation [3]. Scientific studies have confirmed numerous benefits that range from gut, liver and kidney protection to lowering inflammation and cholesterol. 1990;103(10):788-793. Theres also a chance it could interact with other medications. According to a meta-analysis of 16 clinical trials with over 900 people, rhubarb used with standard treatment is effective and safe for reducing pancreatic inflammation [25]. National Library of Medicine Complement Ther Med. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. His mission is to bridge the gap between science and everyday life, helping readers improve their health and feel better. J.Tradit Chin Med 1980;21(11):18. Its stalk is commonly eaten. [Long-term treating effects of rhubarb and captopril in delaying the progression of renal failure]. Required fields are marked *. Aloe-emodin can also act as a laxative [8]. Information is shared for educational purposes only. Clipboard, Search History, and several other advanced features are temporarily unavailable. "Water pills" can also decrease potassium levels. Taking these products together might cause potassium levels to drop too low. More recently, it was uncovered that Rhubarb can also alleviate symptoms of menopause and sepsis, a life-threatening response to infection [4, 5, 6, 7]. **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy. Biol Pharm Bull. 2020;44(6):1066-1078. - 1 tbsp flaxseed. Albrecht UW. Mitsuma, T., Yokozawa, T., Oura, H., and Terasawa, K. [Rhubarb therapy in patients with chronic renal failure (Part 2)]. Song, H., Wang, Z., and Zhang, F. [Investigation of urinary interleukin-6 level in chronic renal failure patients and the influence of Rheum palmatum in treating it]. Mohtashami L, Amiri MS, Ayati Z, Ramezani M, Jamialahmadi T, Emami SA, Sahebkar A. Adv Exp Med Biol. View abstract. Menolabs claims that taking the probiotic can help reduce menopause symptoms. We have all heard stories about rhubarb and bad joints and theres a truth in some of the homespun wisdom the plant is high in oxalic acid, which is reputed to inhibit the absorption of iron and calcium and can also aggravate joint problems, such as arthritis. However, there are several claims that consuming rhubarb for a long time may result in bone loss, muscular weakness, irregular heart rhythm and potassiumloss. The dosage of ERr 731 (rhapontic rhubarb) is 1 tablet/day. The extracts were effective against resistant strains, too [58]. This list does not cover all possible side effects. Safety and efficacy of NT, an herbal supplement, in treating human obesity. Wu, C. X. Altern Ther Health Med. View abstract. Clinical trials used doses ranging from 50 mg to 50 g/day, depending on the disease, type of extract, and other factors. Electronic Code of Federal Regulations. Rhapontic rhubarb is used for many of the same reasons as black cohosh, and it's the active ingredient in the popular menopause supplement Estroven. Gastroenterology 2018;154(4):1096-1101. Comment * document.getElementById("comment").setAttribute( "id", "a269cd1e8bbff3968ad1d173ca7d8400" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. View abstract. Zhang, Z. J., Cheng, W. W., and Yang, Y. M. [Low-dose of processed rhubarb in preventing pregnancy induced hypertension]. View abstract. Rhapontic rhubarb is used for many of the same reasons as black cohosh, and its the active ingredient in the popular menopause supplement Estroven. Syrian rhubarb syrup (2.5 5 mL) along with an antibiotic (ceftriaxone) reduced fever, diarrhea, and the duration of stomach pain in a clinical trial of 150 children with an intestinal infection. Epub 2009 Jul 3. Goel V, Cheema SK, Agellon LB, and et al. 2021 Apr-Jun;12(2):175-179. doi: 10.4103/japtr.JAPTR_324_20. In case you hadnt noticed (fat chance! The doses for rhubarb widely vary. Ji, S. M., Li, L. S., and Ji, D. X. After 84 days, the rhubarb extract reduced menopausal symptoms by 60%. Zhong.Xi.Yi.Jie.He.Za Zhi. J Crit Care. Rhubarb is a type of laxative called a stimulant laxative. In a meta-analysis of studies with nearly 1,000 participants, Chinese herbal mixtures containing rhubarb, in addition to conventional medication, helped patients recover from strokes by reducing the severity of their post-stroke symptoms [47]. In a clinical trial of 80 people with this disease, 30 g/day of Chinese rhubarb was able to reduce fluid buildup in the lungs [51]. Postmenopause is the stage after menopause. Kaszkin-Bettag M, Beck S, Richardson A, Heger PW, Beer AM. It appears to have some benefits for the treatment of menopause symptoms ( 26 ). Soy-free, hormone-free, vegetarian, non-GMO formula provides comprehensive menopause relief. Joint pain reduction. [A preliminary study on the effect of a single Rheum officinale in heavy doses in the treatment of acute icteric hepatitis]. No clinical evidence supports the use of rhubarb for any of the conditions listed in this section. 1-30-1992;62(596):23-25. Gut bacteria then break them down into active metabolites, which reduce the amount of water the colon reabsorbs. Rhubarb has been used for centuries and is especially important in Traditional Chinese Medicine (TCM), which considers it a vital remedy for various diseases. This fools the body into thinking that theres enough estrogen available, stopping or decreasing the symptoms. Rhubarb has been traditionally used to heal a wide variety of issues such as constipation, fever, inflammation, and kidney failure. The special extract ERr 731 from the roots of rhapontic rhubarb has been regularly prescribed for women with menopausal symptoms since 1993. While night sweats are not a common side effect of Estroven Complete menopause supplement, they have been reported in some cases. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Zhou, H. and Jiao, D. [312 cases of gastric and duodenal ulcer bleeding treated with 3 kinds of alcoholic extract rhubarb tablets]. Rhubarb is the name used to describe several plant species in the genus Rheum, native to China, Iran, Turkey, and India. Note: Results may vary about any product effectiveness. Evaluation of the efficacy and safety of Rheum rhaponticum root extract (ERr 731) for menopausal symptoms in perimenopausal Indian women: an interim analysis. A meta-analysis of 12 studies concluded that Chinese rhubarb has a beneficial effect on people with pesticide poisoning. Shanxi Journal of Nursing 1997;11(6):262-263. View abstract. Medicinal value of rhubarb Cooking rhubarb increases its polyphenol content and overall antioxidant capacity. I suffered a small bout of kidney stones, which is rare. In some people, rhubarb can cause diarrhea. Stay up to date with the latest health information from experts/contributors at Consumer Health Digest. Multiple human studies have shown that Siberian rhubarb extract significantly reduces all 11 of the recognized menopausal symptoms. View abstract. Zhu, W., Wang, X. M., Zhang, L., Li, X. Y., and Wang, B. X. Pharmacokinetic of rhein in healthy male volunteers following oral and retention enema administration of rhubarb extract: a single dose study. Special Precautions and Warnings It's usually well-tolerated. (Chinese Journal of Modern Developments in Traditional Medicine) 1984;4(2):88-89. government site. Note that each number in parentheses [1, 2, 3, etc.] 2015 Mar;12(1):61-9. Rhapontic rhubarb or false rhubarb ( Rheum rhaponticum L.) Syrian rhubarb ( Rheum ribes L.) Snapshot Proponents: May help with liver and kidney diseases Relieves menopausal symptoms and menstrual pain Boosts gut health Helps with sepsis and pesticide poisoning May support stroke recovery May lower cholesterol and blood pressure Skeptics: Infantile cholestatic hepatitis syndrome is a rare genetic disorder that causes bile build-up in the liver of newborns. Rhubarb has a laxative effect, but a study published in the Journal of Ethnopharmacology found that it also has antidiarrheal effects because of its tannin content. There is a search provided where you can find either an in-person or an online shop to buy Estroven, presumably at the price they have listed. Select a condition to view a list of vitamins. You are covered by the return policy of the third-party website where you buy the product, however, this manufacturer also has a return policy. 2005 Sep-Oct;12(5):589-600. doi: 10.1097/01.GME.0000156348.61767.D5. The key ingredient in Estrovera is a phyto-estrogen from the Siberian rhubarb plant known as ERr 731, which has been shown to: Reduce the number and severity of hot flashes and night sweats about as effectively as low-dose estrogen. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. 2000;20(2):107-109. Pregnancy can temporarily cause high blood pressure. I am currently continuing at SunAgri as an R&D engineer. In a clinical trial of 126 people with severe inflammation of the pancreas, the use of Chinese rhubarb powder (15 g, 1 2x/day) with a specific nutrition plan lowered inflammation, disease severity, and liver and kidney damage [26]. While many plants contain oxalates/oxalic acids in varying amounts, rhubarb leaves contain very high concentrations of these toxic compounds, making them unsafe for consumption. Spraying rhubarb powder solution under gastroscope in the treatment of acute non-varicose upper gastrointestinal bleeding: A systematic review and meta-analysis of randomized controlled trials. NCI CPTC Antibody Characterization Program. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Medicine (Baltimore). [Clinical study on niaodujing in treating chronic renal failure]. Our goal is to not have a single piece of inaccurate information on this website. Low potassium levels can increase the risk of digoxin side effects. Estroven Complete can reduce the frequency of hot flashes by 80%. Xu, F. and Fu, H. M. [Qing-shen tiao-zhi tablet in the treatment of hyperlipemia in the middle and old aged]. I have a brand new unopened box of it and if you would like it text me at 412 265-5865 or email me at