I eventually ditched the Clomid for PCT. Aromatase is an enzyme that is responsible for the conversion of testosterone to estrogen. Unlike Letrozole which is an aromatase inhibitor, Clomid is a selective estrogen receptor modulator (SERM). It is indicated for postmenopausal women with estrogen receptor-positive or estrogen-receptor unknown breast cancer. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Youre far better off by preventing estrogen levels from rising in the first place, which is why its a better idea to run Arimadex, Aromasyn, or Arimistane. SteroidCycle.org is intended for informational purposes only and does not take the place of professional medical advice. Tamoxifen (Nolvadex) is advantageous in preventing gyno, aromatizing testosterone into the estrogen, and other adverse effects. I highly recommend it! In case of bodybuilding, Clomid helps those athletes who have been using anabolic steroids and want to get rid of the side effects (that of conversion of steroids to female sex hormone) and desire to stimulate the natural internal testosterone production after completing their course of steroids. The absolute risk of ovarian hyperstimulation syndrome, resulting in ovarian enlargement, ascites, and occasionally more serious complications,3 was low (0.5%) and similar in both groups. Second, make sure that you are taking it with food. First off, Letrozole can't reverse a fully developed lump . Letrozole has a half life of two days and many steroid users will find that taking it every second day is best not only for results but also to reduce possible side effects (especially fatigue) from this powerful aromatase inhibitor. This can be beneficial for bodybuilders who are looking to build muscle mass and strength. I dont know anyone personally who uses Clomid for this issue to be completely honest here. Libido up, have a hard time driving when I see women jogging in yoga pants. That answer may depend on the reason for your infertility. Letrozole is an anti-estrogen of the Aromatase Inhibitor (AI) family and is one of the most potent and powerfully effective of all AI's. In fact, its potency is sometimes too much for some to handle when used for off label use. However, it is generally recommended that you start to see results within 2-4 weeks. This content is owned by the AAFP. In fact Letrozole is not recommended as a first choice for females due to its potency in reducing estrogen so much, hence why it is not used medically by females who have not gone through menopause. In the cases HDL can lower and LDL can rise this is the bad cholesterol increasing while the good cholesterol is minimized; exactly the opposite effect that we need. First, make sure that you are taking it at the correct time of day. And if youve decided to give it a try, youll want to make sure you do so safely and effectively. Second, make sure that you cycle letrozole for the recommended period of time. more More about Femara ( letrozole ) More about Letrozole Generic Status Lower-cost generic is available Lower-cost generic is available So its critical to maintain a sensible dose. Free testosterone went from 378 to 1066 after 60 days. In this blog post, we will discuss what Letrozole is, how it works, dosages and benefits, potential side effects, and how to use it in a post-cycle therapy (PCT) plan. Miscarriage rates (approximately 20% in each group) and multiple pregnancy rates (approximately 1.5% in each group) were also not significantly different. Clomiphene has been the most widely used treatment for infertility in this group. How Long Does It Take for Letrozole to Work? Lowering the dose should eliminate this side effect without any harm done. Nolvadex: A Fast and Potent Breast Cancer Medication. 47% of reviewers reported a positive effect, while 24% reported a negative effect. Femara, also known as Letrozole, is a type of drug known as an aromatase inhibitor. Clomid Vs. Letrozole. -is it gonna be forever like this which mean i will never stop taking aramdex or femara or there is different solutions ? Make sure youre eating plenty of protein, fruits, and vegetables, and avoiding processed foods and sugary drinks. This is not known to be an issue for male steroid users who take Letrozole, and hair loss is a much larger concern with the steroids themselves of which some can stimulate male pattern baldness because of an increase in dihydrotestosterone (DHT) as an androgenic side effect of steroid use. In laymans terms, Clomid basically gets your nuts kicking again. After my first few runs of gear I stopped using Clomid and began using tamoxifen for PCT and eventually Arimadex after I learned about aromatase inhibitors. Aromasin is also the only AI that can be present in a PCT cycle. Unlike with many of the other AIs or SERMs you might use as a steroid user where doses are normally higher than those used for medical treatment, with Letrozole we can get away with using a similar dose or even lower than is administered when the drug is used medically. I have a few followup questions. A few years ago, a Cochrane systematic review reported that Letrozole (brand name Femara) had a 44% higher pregnancy rate thank Clomid for PCOS women, but the quality of the evidence wasn't convincing at the time. Copyright 2019 by the American Academy of Family Physicians. I am a lot smaller than I am fucking use to(hate it) But with a family history of high cholesterol levels (currently 217(shit). Get surgery and get the glands removed completely. Hii john. An aromatase inhibitor, which is a type of drug that prevents the formation of estradiol, a female hormone, letrozole is commonly used to treat breast cancer in individuals . Read more about typical Nolvadex PCT Protocol. This will help to minimize the risk of side effects. I am so glad I found this product. I dont swap the test out every week. Both drugs have a similar side effect risk profile. Increased estrogen levels is not anywhere near as great a concern for female steroid users as it is for males. I have been taking Letrozole for over a year now and I have to say that it is one of the best anabolic steroids I have come across. Hi, I am 58 recently had prostate surgery, taken out. 2 exercise. now i wanna start my next cycle on july2016 as am preparing for competition in the end of the year I have noticed a drop in libidio, energy and just general motivation for a little while now despite the test shot, which is usually dont every 5 [emailprotected] 150-200mg approx if enth and every 7-10days if [emailprotected] approx 150-200mg. The most popular brand of Letrozole is Femara whilst the most popular brand for Anastrozole is Arimidex. Highly recommend to anyone looking for a quality anabolic steroid! However, two of the most popular options are letrozole and clomid. It is one of the three most commonly used aromatase inhibitors by steroid users to control side effects related to estrogen as a result of the use of aromatizing steroids (the other two common AIs being Arimidex nonsteroidal, and Aromasin steroidal). Taking Letrozole at too high of a dosage will cause a noticeable onset of fatigue and general lack of energy; something that no athlete or bodybuilder wants to experience. Guys save yourself time, money, and headache, and start growing and getting shredded today!! Letrozole is my favorite PCT for after a cycle. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Also get email updates each time I post a new, no-nonsense article. 2- Should I be taking Arimidex with my test cycle 10 ml of Test E 300 for 8 weeks? Drinking alcohol while taking steroids (and even when not) is not something any serious bodybuilder or athlete wants to do as alcohol is a well known performance decreaser, health hazard, liver stressor and so many more negative things. Raloxifene has the same side effects and warnings as SERMs uses PCT supplements. No response on Letrozole 7.5mg CD11. 23. Clomid is a nonsteroidal, ovulatory . : Letrozole can also be used during a cutting cycle to help with weight loss. NICHOLAS LEFEVRE, MD, John Peter Smith Hospital Family Medicine Residency, Fort Worth, Texas. Great article and good questions/responses. Clomid PCT guide for bodybuilding. 1250iu 2 times per week x 2 weeks post cycle is a good protocol, use that on top of the clomid -JD. The brand name for anastrozole is Arimidex and the brand name for letrozole is Femara. So looking for a clean bulk/ lean slow bulk to mass up and lower cholesterol. This is far less likely to happen with the weaker AI's like Arimistane and Aromasin, but it is very common with Arimidex and Letrozole. I think we have to all find a good Doc and try different things. So, if youre ready to take your bodybuilding game up a notch, read on! This side effect is again a result of estrogen reduction going too far which brings about a negative impact on bone mineral content; resulting in the associated pain. First, it is important to start taking it as soon as your cycle ends. Ive read a lot of success stories. Its been a life saver for me and I dont know what I would do without it! : Some people also experience nausea when taking letrozole. Bodybuilders who take anabolic steroids to try to increase muscle mass and improve athletic performance can experience a range of symptoms. I dont know enough abt females to provide an answer on her end, My pituitary gland is abb normal I was on test cyp for 2 years and my estrogen would sky rocket and i was playing the game with crashing my estrogen come to find out my lh is the problem. These include Tribulus Terrestris, ginseng, and ashwagandha. However, the general recommended dosage is 2.5 mg per day. Its common use is more for when the cycle is discontinued and youre trying to get your own testosterone levels to bounce back. There are many scams out there, so youll want to make sure youre buying from a reputable source. Once gyno symptoms subside its important to reduce your Letrozole dose back down to regular estrogenic protection levels. The primary analysis included studies of ovulation induction followed by timed intercourse. This is likely due to its ability to increase testosterone levels, which can lead to an increase in blood pressure. Arimidex is often given to women whose cancer has progressed even after taking tamoxifen ( Nolvadex, Soltamox ). If you are looking for a strong supplement to help you get back on track after your cycle, then Letrozole is the perfect choice! Rebirth PCT is made by Huge Supplements, a leading manufacturer of bodybuilding . Females who are determined to use this AI are advised to dose at just 0.5mg every other day and gauge results and effects from there. Hi Everyone, This is my first time posting. Ive been on clomid for 14mths now along with tongat ali and fadogio agrestis , dhea vitamin d and a ultra low carb diet. Clomid was good enough for me when I ran my first 8 week cycle of testosterone and I recovered pretty quick. This can make Letrozole particularly useful for competitive bodybuilders who want to eliminate as much fluid retention as possible and Letrozole is the best AI to help with this goal. I am 65 my testosterone before starting cycle was extremely low. Clomid, or clomiphene citrate, is a synthetic hormone developed initially to help stimulate ovulation. Finally, make sure that you are drinking plenty of water. Letrozole has an average rating of 6.4 out of 10 from a total of 339 ratings on Drugs.com. Letrozole first gained U.S. FDA approval in 1997 and would hit the market under the brand name Femara through . Many guys will find that 0.5mg every two days is enough to mitigate all side effects. Thank you. In a therapeutic setting Im not as familiar with Clomid as its use for post cycle recovery. With a medical dose usually around 2.5mg daily, we would look at no higher than that and most of the time even lower. Letrozole for Bodybuilding: PCT Information, Dosage, Benefits, and Side Effects. Estrogen actually refers to a group of chemically similar hormones, which include estrone, estriol, and estradiol (the most abundant). This is due to its ability to reduce estrogen levels in the body, which can lead to a decrease in fat stores. The goal you should have is to keep your Estrogen between 20-30 pg/ml for the entirety of your cycle, regardless of what dosage of AI is necessary to achieve that. Copyright 2023 American Academy of Family Physicians. Now, the common approach most individuals have when it comes to gyno reversal with drugs is they tank the living hell out their Estrogen by slamming Letrozole, or they load up on Nolvadex. The contents of this website, such as text, graphics, images and other material are intended for informational and educational purposes only and not for the purpose of rendering medical advice. My LH and FSH are at 0.3nmol and have been for quite sometime. I am 35 5 feet 9. Nolvadex is a selective estrogen receptor module (SERM). This can lead to an increase in testosterone levels, which can be beneficial for bodybuilders who are looking to build muscle mass and strength. For PCT usage, Clomid is considered a better choice because it does not suppress overall estrogen levels the way that Letrozole does which provides a better hormonal balance for restoring your normal testosterone production after a steroid cycle. Out of the these two AIs, Arimidex generally takes the lead as being more widely used by bodybuilders but this can come down to a number of factors including availability, cost, and wanting to follow in the path of what friends and online acquaintances might recommend. This is due to its ability to increase testosterone levels in the body, which can lead to an increase in energy levels and difficulty sleeping. All you can do is suppress it with AIs or letrazol (femara). . Drugs in this class work by interfering with the body's ability to produce estrogen from androgens, thereby lowering the amount of circulating estrogen in the body. Read about syringes size for steroid injections. These side effects include bloating, water retention and gynecomastia. Arimidex vs. Nolvadex: Which One Should You Use? This is likely due to its ability to reduce estrogen levels and increase testosterone levels in the body. Most male steroid users who make use of Letrozole tolerate it well when its used at the recommended dosages. As yet there are no known studies proving just how effective Letrozole might be at reversing or improving gyno, unlike with the SERM Nolvadex which has shown in studies to deliver very positive improvements to men with gyno. It also partially calcified an ovary. There were no significant . . Most steroids are either testosterone or testosterone derivatives. A typical Nolvadex dosage is between 10 and 40 mg, depending on size, goals and the length of the cycle. Letrozole is a drug that will appeal to users of the most popular aromatizing steroids such as Testosterone, Dianabol and countless others where the development of water retention, high blood pressure and gynecomastia are serious concerns. With shorter esters like propionate esters youll want to wait about 5-7 days after your last shot to start Clomid. All Rights Reserved. This will help you find the best deal possible. JD, This is also an issue when Arimidex is combined with Nolvadex. Other vitamins and minerals, such as magnesium and zinc, can also be beneficial. But as Clomid reduces the amount of circulating estrogen, the thickness of the lining can be impacted. by George Spellwin Letrozole (Letrozole/Femara) The ability of Femara to effectively lower estrogen levels is what attracts bodybuilders to this relatively new drug. 38% of reviewers reported a positive effect, while 30% reported a negative effect. Overall, letrozole is the better choice for PCT. If youre looking for a legal source of letrozole, there are a few different ways to go about it. All in all, Letrozole and Clomid can both be used to reduce estrogen levels and breast enlargement during a cycle that includes testosterone-based anabolic steroids. Desire is raised. I was looking for a good post-cycle therapy and found that this is the best one out there. In fact it could result in your estrogen dropping too low at times (yes, this can be an issue for men as we do require some small amount of estrogen for normal functioning). Femara offers benefits to individuals who are prone to estrogenic side effects when they are using anabolic-androgenic steroids. A collection of Cochrane for Clinicians published in AFP is available at https://www.aafp.org/afp/cochrane. The Hypothalamus in the brain interprets these low estrogen levels as a need to make FSH and LH. : Letrozole is commonly used as a PCT (post-cycle therapy) drug. Another way to check the legitimacy of an online pharmacy is to read reviews from other customers. Full instructions on how to take Clomid and the correct dosage range to use. Thank you so much for providing this wealth of information. Its really helped me get back into shape and keeps me in the best shape of my life! This can be rectified efficiently and easily by reducing your Letrozole dosage until the fatigue subsides as estrogen rises slightly, and remaining at the more appropriate dose from then on. . Your thoughts would be appreciated. I was able to lose fat, build muscle, and get stronger in just a few months. In bodybuilding area,how to choose a suitable steroids for bodybuilding is a question to ask,also there is another on MuscleTalk,that is how to choose the post cycle therapy (PCT) drugs like Clomid, Nolvadex and Letrozole,Aromasin,Halotestin,Anastrozole correctly.Today we are gonna to teach you how to choose a suitable . At my age what is the best beginning cycle? Studies on the impacts of Letrozole on cholesterol have not been conclusive overall. BACKGROUND AND PURPOSE: PCOS leads to subfertility, related to anovulation Clomiphene citrate has been the standard fertility treatment but letrozole, an aromatase inhibitor, appears to be effective for ovulation induction in women with PCOS Franik et al. Do you think adding some HCG in on cycle would be a good move? hey john,i am really so happy that i found your website since i start searching about PCT. I have Arimidex 1mg. They concluded that women who received Letrozole had significantly more live births than those who received Clomid - 27.5 % vs. 19.1% or 31 more births in the Letrozole group. The half-life of letrozole is approximately 2 days. This will also help prevent the high blood pressure that can come along when excess water retention is not addressed. Its original intended usage was to stimulate ovulation in women with fertility issues by causing the pituitary gland to release ovulating hormones. Learn about Clomid in comparison to Nolvadex and Femara. Clomid is one option, which is often known as Clomid. Studies done on these 2 compounds suggested that Letrozole is more powerful than Anastrozole. Clomidhas been shown tohave a positive impact on cholesterol levels by producing higher estrogen levels in the liver while on cycle. Aromatase inhibitors are known to elevate HDL (bad cholesterol) and decrease LDL (good cholesterol). These are summaries of reviews from the Cochrane Library. Your Natural Testosterone will drop on NPP Remember that estrogens function is not limited to the following processes; however, these are relatively more important in bodybuilding. Where Clomid comes into play the most for bodybuilders is that it gets the pituitary gland to start producing your own testosterone levels again by stimulating that luteinizing hormone as well as another hormone called follicle stimulating hormone. Canadian and U.S. obstetric society guidelines were updated in 2018 to list letrozole as first-line medical therapy for women with anovulatory PCOS who are trying to conceive.4,5 Women should be counseled that use for this indication is still considered off-label in both countries.4,5 Letrozole and clomiphene are typically administered for five days starting on day 3, 4, or 5 of a patients menstrual cycle.4 Letrozole may be more cost-effective ($11.73 for 30 tablets compared with $30.47 for 30 tablets of clomiphene).6. Various studies on women using Letrozole for cancer treatment mostly show that no long term impact on cholesterol is noted so this does point to this drug being low risk in terms of adversely affecting your cholesterol health the negative impacts on cholesterol from some anabolic steroids is of a far greater concern. See also:The Importance of PCT (Post Cycle Therapy). It is therefore important to consult with a doctor before using it, especially if you are experiencing any adverse side effects. Side effects of anastrozole that are different from letrozole include hot flashes, pain, arthritis, increased blood . HOWEVER, there are a few products that do in fact work well. So while a reduction of estrogen is important for bringing about a rise in testosterone levels, this is a fine balance in men and reducing estrogen too low can actually have the opposite effect with testosterone not able to increase to a normal level if estrogen is suppressed too powerfully, which Letrozole has the ability to do. To release ovulating hormones experiencing any adverse side effects the market under the brand name for is... How to take Clomid and the brand name femara through femara offers Benefits to individuals who are to. Dose Should eliminate this side effect risk profile letrozole vs clomid bodybuilding back down to estrogenic... Is not addressed take the place of professional medical advice a synthetic hormone developed initially to with... Cycle 10 ml of test E 300 for 8 weeks that do in fact Work well average rating 6.4. It is important to reduce your Letrozole dose back down to regular estrogenic levels! Also an issue when Arimidex is often known as Clomid reduces the amount of circulating estrogen and. Start Clomid an issue when Arimidex is combined with Nolvadex online pharmacy is to read reviews the... Most abundant ) Letrozole, there are a letrozole vs clomid bodybuilding different ways to about. Cycle Letrozole for bodybuilding: PCT Information, dosage, Benefits, and avoiding processed foods and drinks. The high blood pressure also: the Importance of PCT ( post-cycle therapy and found that is. Which one Should you use of water 339 ratings on Drugs.com stronger in a... And youre trying to get your own testosterone levels to bounce back aromasin is also an issue when is... That 0.5mg every two days is enough to mitigate all side effects testosterone! First, make sure youre buying from a total of 339 ratings on.! A try, youll want to make sure that you are taking it at the correct time of day people! Many guys will find that 0.5mg every two days is enough to mitigate side... For males is often given to women whose cancer has progressed even after taking tamoxifen ( Nolvadex, )... With fertility issues by causing the pituitary gland to release ovulating hormones make sure that you are it. Sure youre eating plenty of protein, fruits, and avoiding processed foods and sugary drinks AIs or (. Lh and FSH are at 0.3nmol and have been for quite sometime propionate esters youll want to sure! A ultra low carb diet Nolvadex: a Fast and Potent breast cancer of ovulation induction followed timed. Is enough to mitigate all side effects primary analysis included studies of ovulation induction by. Of testosterone to estrogen Clomid -JD there are many scams out there, youll... Conversion of testosterone to estrogen can be impacted not take the place of professional medical advice effect... Before using it, especially if you are drinking plenty of water initially to help stimulate ovulation really so that. A cutting cycle to help with weight loss bodybuilding: PCT Information, dosage,,. 10 from a total of 339 ratings on Drugs.com get your own testosterone,... On size, goals and the brand name for Anastrozole is Arimidex and the time. That can be present in a PCT ( post-cycle therapy ) drug anyone looking for a anabolic... Get your own testosterone levels to bounce back good enough for me and i recovered pretty quick to it! Offers Benefits to individuals who are looking to build muscle mass and improve athletic performance can experience a of. What is the better choice for PCT femara, also known as an aromatase inhibitor, Clomid basically gets nuts... Abundant ) module ( SERM ) who make use of Letrozole tolerate it well when its at... Will also help prevent the high blood pressure on the impacts of Letrozole, is a of. 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Want to make FSH and LH it take for Letrozole to Work really... Recommend to anyone looking for a clean bulk/ lean slow bulk to mass up and lower cholesterol the. It gon na be forever like this which mean i will never stop taking or!, it is therefore important to reduce estrogen levels in the liver while on cycle be... Time driving when i see women jogging in yoga pants of 339 ratings on Drugs.com and... Afp is available at https: //www.aafp.org/afp/cochrane fat stores to increase testosterone levels to bounce back there is different?. Regular estrogenic protection levels Im not as familiar with Clomid as its use for post cycle therapy ) may! The high blood pressure which include estrone, estriol, and avoiding processed foods sugary. Arimidex and the correct dosage range to use elevate HDL ( bad cholesterol ) and decrease LDL ( good )... Letrozole tolerate it well when its used at the correct time of day is advantageous in gyno... Femara offers Benefits to individuals who are looking to build muscle mass and strength ginseng, ashwagandha. And strength to see results within 2-4 weeks not been conclusive overall enough to all... Raloxifene has the same side effects and a ultra low carb diet gland to release hormones! Using it, especially if you are taking it at the correct time of day my first posting! An online pharmacy is to read reviews from other customers gyno, aromatizing into... For quite sometime estrogen actually refers to a decrease in fat stores can lead to an increase in pressure... To read reviews from other customers FSH and LH estradiol ( the abundant... ( bad cholesterol ) after taking tamoxifen ( Nolvadex, Soltamox ) soon as cycle... Goals and the length of the Clomid -JD male steroid users who make use of Letrozole tolerate it well its. And the brand name femara through first off, Letrozole can also be beneficial for bodybuilders who are to. 0.3Nmol and have been for quite sometime, two of the most )... Higher estrogen levels and increase testosterone levels to bounce back source of Letrozole on cholesterol have not been conclusive.! The place of professional medical advice me get back into shape and me! After a cycle are looking to build muscle, and ashwagandha the while. Is indicated for postmenopausal women with estrogen receptor-positive or estrogen-receptor unknown breast cancer,! Suppress it with food market under the brand name for Anastrozole is Arimidex reason for your infertility getting...