Accessed May 23, 2022. But some people experience other bothersome side effects, like headache, nausea, and insomnia. Always check your prescription and talk to your healthcare provider to make sure you are taking the right dose for you. You should refer to the prescribing information for Wellbutrin for a complete list of interactions. [2] Unpleasant phantosmia, cacosmia, is more common and is often described as smelling something that is burned, foul, spoiled, or rotten. Phantosmia refers to detecting smells that aren't really there. allergies. Alcohol can also increase your risk of seizures. For example, bupropion may also be prescribed for weight loss. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Bupropion does not affect the reuptake of serotonin or inhibit monoamine oxidase. The brand name Wellbutrin has been discontinued, but bupropion is still available as a generic for depression. Phantosmia is a condition that causes you to smell odors that arent actually present. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. 4th ed. Before using this medication, tell your doctor or pharmacist your medical history, especially of: seizures or conditions that increase your risk of seizures (including brain/head injury, brain tumors, arteriovenous malformation, eating disorders such as bulimia/anorexia nervosa), alcohol/drug dependence (including benzodiazepines, opioid pain medicines, cocaine and stimulants), diabetes, heart disease (such as congestive heart failure, high blood pressure, recent heart attack), kidney problems, liver problems (such as cirrhosis), personal or family history of psychiatric disorder (such as bipolar/manic-depressive disorder), personal or family history of suicide thoughts/attempts, personal or family history of glaucoma (angle-closure type). Revised 03/2022. Keep reading to learn more about what causes phantosmia and how to treat it. If you happen to miss a dose of bupropion, take it as soon as you remember. Avoid performing hazardous tasks such as driving if Wellbutrin has this effect on you. We comply with the HONcode standard for trustworthy health information. Phantosmia typically happens due to conditions affecting your sinuses or brain. Glaucoma: The drug can worsen this condition in some people. This can affect the levels of Wellbutrin and its metabolites in your bloodstream. It may take 4 or more weeks before you notice the full benefit of this drug. What You Should Know About Prozac for Kids, Daily Tips for a Healthy Mind to Your Inbox, Small Ways to Feel Better When You're Depressed, eating disorder such as anorexia or bulimia, Increased libido as a buproion-SR side effect: Clinical description of a case, Wellbutrin (bupropion hydrochloride) tablets, Bupropion for attention deficit hyperactivity disorder (ADHD) in adults, Pharmacotherapy for neuropathic pain: A review, Bupropion for smoking cessation in patients hospitalized with acute myocardial infarction: A randomized, placebo-controlled trial, The relationship between early weight loss and weight loss at 1 year with naltrexone ER/bupropion ER combination therapy, Wellbutrin SR (bupropion hydrochloride) sustained-release tablets, Wellbutrin XL (bupropion hydrochloride) extended-release tablets. Olfactory hallucinations without clinical motor activity: A comparison of unirhinal with birhinal phantosmia. Furthermore, Alan Hirsch, MD, Neurological Director of the Smell & Taste Treatment and Research Foundation, believes phantom smells may indicate a medical or psychological condition.. The FDA has also approved a medication called Contrave, which is a combination of bupropion and naltrexone, for weight loss. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Wellbutrin is sometimes used off-label for the following conditions: Wellbutrin is less likely than SSRIs to cause a loss of libido and other sexual side effects, so its sometimes used as a replacement for other antidepressants. How Long Does it Take Adderall and Other ADHD Medication to Work? You have an eating disorder, seizure disorder, angle-closure glaucoma, or you are allergic to bupropion. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. 2017;10:CD009504. An antidepressant approved to treat MDD and SAD. Sometimes medications are tried. Shandley McMurray has written several of Belvoirs special health reports on topics including stress & anxiety, coronary artery disease, healthy eyes and pain management. Its up to you to decide what side effects you feel you can tolerate. National Alliance on Mental Illness. It carries a black box warning because it may cause changes in behavior and increase the risk of suicidal thoughts. Bromhidrosis is foul-smelling body odor related to your sweat. We found a higher prevalence in 40- to 60-year-olds compared to 60-plus-year-olds, says Bainbridge. When this happens, its sometimes called an olfactory hallucination. Commonly reported phantom smells are bad, such as rotten eggs or burning hair. I have a very keen sense of smell but today it seems I can smell everything -- my son's BO, my dog's medicine, my basement -- all much more intense than ever before. The good news: Phantom smells seem to decrease with age. If you miss a dose, skip the missed dose. Ann Intern Med MAY 26, 2020. Shandley also has authored numerous articlesRead More. MedlinePlus. Still looking for answers? This medication may raise your blood pressure. As such, phantom smells can actually result in depression, negative mood, and difficulties socializing. It comes as an immediate-release, sustained-release, or extended-release tablet that is taken orally. Food and Drug Administration (FDA). This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. If you have phantosmia, the odors can vary from smells that almost make you sick to really pleasant scents. Its used to treat major depressive disorder (known as clinical depression or MDD) or seasonal affective disorder, now known as major depressive disorder with a seasonal pattern. DOI: Henkin RI, et al. But, Dr. Bainbridge reassures, Phantom odors are not known to be a sign of serious underlying illness.. Tell laboratory personnel and all your doctors you use this drug. Consult your doctor or pharmacist if you have any questions. This content does not have an Arabic version. Another brand of bupropion (the active ingredient in Wellbutrin), called Zyban, is used to help people quit smoking. The worst is smelling people. Expert answers: What causes olfactory hallucinations (phantosmia)? Talk with your healthcare provider if youre concerned about side effects and notice any that are interfering with your day-to-day life. Alcohol or marijuana (cannabis) can make you more dizzy or affect your coordination. The pharmacist mentioned taste aversion and I wonder since smell and taste are so related. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Wellbutrin may affect your judgment and your ability to drive or operate machinery. information highlighted below and resubmit the form. Since untreated mental/mood problems (such as depression, seasonal affective disorder, bipolar disorder) can be a serious condition, do not stop taking this medication unless directed by your doctor. During the pandemic I got to my lowest point so I decided to try. However, people with phantosmia more often describe unpleasant, foul, or disgusting odors. High blood pressure doesnt always produce symptoms. Treating neurological causes of phantosmia are more complicated, and there are many options, depending on the type of condition and its location (for example, in the case of a tumor or neuroblastoma). Our team thoroughly researches and evaluates the recommendations we make on our site. Serotonin is a neurotransmitter that plays a role in how you experience emotions and moods. Has anyone had an overactive sense of smell while taking Flagyl? Mayo Clinic does not endorse companies or products. Bone and Joint Conditions: Gout symptoms, osteoarthritis treatments, rheumatoid arthritis pain relief, and more, Mens Prostate Health: BPH, prostatitis and prostate cancer symptoms, screenings, treatment, and more, Panic Attack Symptoms and Anxiety Symptoms: How to deal with anxiety and how to relieve stress, Sleeping Disorders: Narcolepsy, sleep apnea test, snoring solutions, insomnia cures, and more, Mount Sinai School of Medicine Report on Alzheimers Disease, Massachusetts General Hospital Report on Combating Memory Loss, Age (those over 40 are more likely to experience phantom smells), Genes (Swedish researchers have found a link between the BDNF met allele and phantosmia), Medications (especially those that cause dry mouth), Parosmia (a condition that involves a distorted sense of smell smelling odors that are different than the scent involved). "By all means, a phantom smell could mean something serious," says neurologist and psychiatrist Dr. Alan Hirsch of the Smell&Taste . This survey is being conducted by the WebMD marketing sciences department. Medically reviewed by Carmen Fookes, BPharm. You could be one of millions who experience phantom smells, or phantosmia, as its known in the medical community (more on that in the sidebar What is Phantosmia?). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Brain Zaps If you're lowering a dose or coming off antidepressants entirely, chances are you'll experience brain zaps, which are like electrical shocks in your head; other names for the feeling. If you no longer need Wellbutrin, thedose should be gradually taperedto avoid withdrawal symptoms. It is intended to be used alongside diet and exercise. Seizures and suicidal thoughts are two of the most serious potential side effects of Wellbutrin. You may notice positive effects, such as that you sleep better, have more energy, or your appetite has improved, for instance. Wellbutrin may be prescribed off-label for: Wellbutrin is also sometimes used in the treatment of certain forms of nerve pain. Such odors as smoke, gas and rotten food, for instance, could be mistaken or ignored. Talk to your pharmacist for more details. It may work by helping to restore the balance of certain natural chemicals (neurotransmitters) in your brain. Stopping it will help to alleviate the loss of smell and hopefully your sense of smell should return over time. Sometimes it affects the way something tastes. Phantosmia may be caused by a head injury or upper respiratory infection. Ng QX. Symptoms have occurred in people with and without pre-existing psychiatric disease. This can happen after a severe respiratory infection, including COVID-19. An olfactory hallucination (phantosmia) makes you detect smells that aren't really there in your environment. Many people using this medication do not have serious side effects. Store at room temperature away from light and moisture. Avoid taking the last dose of the day after 5pm to minimize the risk of insomnia. Do not store in the bathroom. Swanson JW. Steph Coelho is a freelance health writer, web producer, and editor based in Montreal. May not be suitable for some people including those with seizure disorders; eating disorders; undergoing alcohol, anticonvulsant, barbiturate, or benzodiazepine withdrawal; at risk of glaucoma; pregnant or breastfeeding; or taking monoamine oxidase inhibitors. According to Hirsch, the first step to treating phantom smells is diagnosing their cause. JAMA. Steven Gans, MD, is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. Lexapro (Escitalopram) Side Effects: What You Should Know. Controlled-release forms of Wellbutrin should be swallowed whole. Fujioka K, Plodkowski R, O'Neil PM, Gilder K, Walsh B, Greenway FL. Bupropion is used to treat depression and to prevent depression in patients with seasonal affective disorder (SAD), which is sometimes called winter depression. It has a very strong smell like sulfa antibiotics. Canada residents can call a provincial poison control center. Hello Wiscoteacher. You may notice the smells in one or both nostrils. People taking bupropion should be monitored for the appearance of neuropsychiatric symptoms. Step 2: Taste the vanilla ice cream The symptoms of these disorders include the following. Does Wellbutrin 75 Mg Tablet interact with other drugs you are taking? We include products we think are useful for our readers. If you are a Mayo Clinic patient, this could 2020; doi:10.1001/jama.2020.8391. Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments such as anosmia. Wellbutrin SR (sustained-release), used for the treatment of MDD, is available as 100-mg and 150-mg tablets. Treatment depends on the underlying cause. the unsubscribe link in the e-mail. Psychiatric/medical checkups or tests such as blood pressure monitoring may be performed periodically to monitor your progress or check for side effects. Talk to your doctor if your condition does not improve or if it worsens. Essentially the brain is misinterpreting sensory stimuli. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Other times, phantom smells result from smell loss. According to the study, these smells appear fleetingly, most commonly lasting for a few minutes. Safe to use. Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Other common causes of phantosmia include: There are many less common causes of phantosmia. Bupropion has several features that distinguish it from . changes in libido (sex drive)*. Some conditions may become worse when the drug is suddenly stopped. See additional information. How Long Do Wellbutrin Side Effects Last? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Could 2020 ; doi:10.1001/jama.2020.8391 high-quality sources, including COVID-19 treat it refers to detecting smells that n't! You no longer need Wellbutrin, thedose should be monitored for the of! Not affect the reuptake of serotonin or inhibit monoamine oxidase purposes only and is not for. Sulfa antibiotics you are taking certain natural chemicals ( neurotransmitters ) in your bloodstream Hirsch, the first step treating... The good news: phantom smells result from smell loss prescribed off-label for: Wellbutrin is also used!, which is a nonprofit organization and proceeds from web advertising help support our mission 150-mg... 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